Posts Tagged ‘malcolm kendrick’

The Clot Thickens, Part 2: Further Momentum Against the Diet-Heart Hypothesis

Dr. Malcolm Kendrick and his book, The Clot Thickens

Heart disease is the number one killer in the US, and some of the advice about preventing it has been dead-on wrong.

Here’s an example. I first wrote about the relationship, or really lack of relationship, between eating saturated fat and both cardiovascular disease (CVD) and coronary heart disease (CHD) in July last year after reading and then listening to Dr. Malcolm Kendrick’s extraordinarily practical The Clot Thickens. I’ve recommended that book to many people and certainly recommend it to you as highly informed guidance regarding your cardiovascular and coronary heart health and quality of life maintenance.

I’m writing about The Clot Thickens again now because there seems to be an even further change in perspective based on new and newly revisited evidence, all supported by legitimate science, that shows that the “diet-heart hypothesis”, which Dr. Kendrick strongly opposes, is false. That hypothesis, since it first came about in the 1950’s, adamantly argues that eating saturated fat increases blood cholesterol levels (which we don’t and can’t have because cholesterol is not water or blood soluble) and therefore is one of the causes of cardiovascular disease (disease to the arteries) and coronary heart disease (disease to the arteries surrounding the heart).

If you read The Clot Thickens or the bullets toward the bottom of the July 2024 piece I wrote, you’ll quickly see why eating saturated fat does not increase cholesterol and that cholesterol cannot cause cardiovascular disease or heart disease. At the same time, you’ll also see that eating saturated fat, which is high in calories, in greater amounts than your body needs to maintain metabolism and cellular structural integrity will be stored as fat in your body. It’s always all about balance. 

Regarding balance, here are 2 powerful examples of the continued erosion of the diet-heart hypothesis, both of which were generated by artificial intelligence. A few days ago, I entered this ChatGPT 4o query: “Does eating saturated fat cause heart disease?” and got the summary response shown below. You can get the whole response in a short PDF by clicking this link.

ChatGPT 4o response to "effect of diet-heart hypothesis on heart disease in America"

Two days ago, I entered this Google query: “effect of diet-heart hypothesis on heart disease in America”.

The first answer to pop up was the Google Generative AI response below that was both more hard-edged than the ChatGPT answer above and included a list of solid references. Again, what you see below is a summary. You can get the full answer by either dialing in the query yourself, which might or might not give you the same answer I got, or you can click this link to see the exact the answer I got.

Google Generative AI response to "effect of diet-heart hypothesis on heart disease in America"

I started the piece I wrote in July with this line about common sense. “Common sense isn’t common until you’re introduced to it. After that you’re on the hook.” I believe that entirely – but only when that common-sense introduction comes from a verified source supported by valid evidence. At the same time, that does not mean that “verified sources” and “valid evidence” are etched in stone forever. Life is about learning and adapting to changes happening all the time. I find that exciting. And to see change coming to pass regarding a significant diet, heart health and quality of life recommendation that’s existed all my life, to me, is an example of positive progress, again thanks very much to the efforts and persistence of people like Dr. Kendrick. 

But, you be the judge. Don’t just buy what I’ve written here. To use a car analogy, pop open the hood, kick the tires and see what you find about what I argue here – and more – and then apply what you’ve learned to your life and, most of all, make it fun and fully flavorful doing it! 

Next up:  Quick & Easy Microwave Warmed Spinach & Apple Salad

Freeing Eggs From a Bad Rap

Bad Eggs

A month ago I wrote about the very undeserved bad rap bananas have gotten. And like I mentioned in that piece, I believed the negative hype and avoided bananas for a while. But life is about learning and adapting. I learned the truth about bananas and very quickly adapted my diet include them again, quite happily – and, actually, just had homemade banana ice cream with full-on flavor for dessert after lunch. Killer!

Picture book directions show how to take homemade banana ice cream from simple to exciting

Along with bananas, there’s another exceptionally popular food that, until very recently, has been unfairly criticized: eggs. Their crime: allegedly raising blood cholesterol and increasing the chances of heart disease. Wrong – and that’s based on objective scientific research, meaning scientific research that is not tainted by industry self-interest. Still, if you query “latest research on eggs and health“, and I urge you to do that on your own – and be sure to check both the source and date of what you find – you will still find continued “good vs. bad” controversy.

Regarding cholesterol, yes, eggs are high in cholesterol and are also extraordinarily rich in protein and other vital nutrients. As Dr. Malcolm Kendrick, author of The Clot Thickens , said in a January 2022 interview you can see by clicking this link or the image below and going to the 4 minute 40 second mark, an egg yolk is so rich in cholesterol “because it takes an awful lot of cholesterol to build a healthy chicken”. (My bold for emphasis.)

Dr. Malcolm Kendrick discusses the health importance of cholesterol

You can read more about Dr. Kendrick and his scientifically-based work by checking out my last blog. As I wrote in that piece, I’ve put his diet and health advice to practice – and love it for the foods I enjoy, how I feel as a young 66 year old and my consistently outstanding blood test results.

Next up: pan fried scrambled eggs – the first thing I ever tried to cook long ago but… Ha! I’m asking you to wait -not too long – to see exactly what that “but” means.

“The Clot Thickens”: Dietary Fat Does Not Cause Heart Disease

Common sense isn’t common until you’re introduced to it. After that you’re on the hook.

But first a warning: just be sure to verify the source of that “common sense” before you believe it, internalize it and put it to practice.

Here’s a prime example regarding food and health. I just Googled “does eating saturated fat cause heart disease”, and this excerpt from MedlinePlus popped up as the first hit.

As stated directly on their website, “MedlinePlus is a service of the National Library of Medicine (NLM), the world’s largest medical library, which is part of the National Institutes of Health (NIH)”.

The only problem with the above excerpt from my Google search, especially considering its influential source and page title, “Facts about saturated fats“, is that it is largely incorrect. Saturated fats are not unhealthy fats. The only stumbling block for me are the vague words “too much” in the highlighted blue section, which then give the word “can” some validity because too much of any food (or anything) can indeed lead to negative consequences. (More about that in the “takeaway” bullets below.)

Here’s what I got when I clicked to read the full page.

Everything underlined in light turquoise is undeniably true. The lines underlined in red, however, are not true based on scientific evidence. Those lines instead support the completely scientifically debunked “diet-heart disease” hypothesis that holds that eating saturated fat can lead to raised cholesterol levels in the bloodstream, which then can lead to arterial wall cholesterol plaque buildup and eventual arterial blood flow obstruction resulting in heart attack, stroke and other associated life-threatening problems.

The reason I’m convinced that the diet-heart hypothesis is wrong – although I completely and incorrectly believed it as common sense for decades – is that I’ve read, listened to and agree with the breadth and depth of evidence laid out in The Clot Thickens by Dr. Malcolm Kendrick, which is a must-read for anyone interested in the causes and prevention of the leading cause of human death, heart disease, or, more specifically, cardiovascular disease/coronary heart disease (CVD/CHD).

Dr. Kendrick is a Scottish general practitioner, who has spent decades rigorously studying CVD/CHD from an evidence-based, biochemical and physiological point of view. Here are some significant takeaways and quotes from The Clot Thickens that overwhelmingly debunk the diet-heart “eating fat leads to heart disease” hypothesis:

  • Most importantly, CVD/CHD is not caused by a single problem but is instead a process problem. (Dr. Kendrick adopted his “process” approach through insight gained from one of his professional mentors, Dr. Paul Rosch, Clinical Professor of Medicine at New York Medical College and Chair of The American Institute of Stress.)
  • No-one actually has any such thing as a cholesterol level…because cholesterol cannot float free in the blood, as it is not water soluble, and therefore cannot be blood soluble. (This is due to) a somewhat inconvenient chemical fact: cholesterol has to be transported (through the bloodstream around the body in microscopic) spheres called lipoproteins (lipid + protein = lipoprotein), which are about the size of a virus.”
  • Heart disease has nothing to do with eating saturated fat“. That means eating a diet rich in saturated fat and cholesterol does not cause cardiovascular disease/coronary heart disease (CVD/CHD). (My personal note: along with what I wrote about “too much” above, Dr. Kendrick’s entirely appropriate statement does not mean you can eat as much saturated fat and cholesterol as you want. Fats (more precisely identified as “fatty acids”) are high in calories, and those fats not used to maintain cell membrane integrity and support energy metabolism are stored in fat cells. Excessive fat storage leads to weight gain. Significant weight gain can then contribute to compounding problems that lead to CVD/CHD.)
  • The root cause of CVD/CHD is clotting (or thrombogenesis), which is why Dr. Kendrick’s book is titled The Clot Thickens. Initial arterial clotting is a multi-staged complex process and is the result of chemical, biochemical, physical and/or particulate matter damage first of the glycocalyx, the slippery blood flow-facing protective lining of arteries, and then subsequent damage to the single-cell-thick endothelial wall. (As defined concisely by US NIH, “Endothelial cells line the entire vascular system, from the heart to the smallest capillary, and control the passage of materials—and the transit of white blood cells—into and out of the bloodstream.”
    • Let’s cut the above bullet into two parts:
      • In the same way that your skin responds to a cut or abrasion by clotting and scabbing over until the skin heals beneath it, your body responds to damage to your endothelial cells, which cannot heal themselves, by initiating the above-mentioned clotting process and then absorbing and dissolving that clot deeper in the arterial wall to complete the healing – unless there are continued added injuries in the same location, which then allow the clot to grow ever-larger and restrict blood flow. A significant component of that multi-phase clotting process involves red blood cells (RBC’s) attaching themselves to a developing clot and thereby fortifying that clot – and here is where cholesterol comes in. RBC cell membranes contain about 40% cholesterol – and that is not unusually high, as all animal/human cell membranes contain on the order of 20-40% cholesterol. Most significantly, though there are other clotting components that also contain cholesterol in their structure (as noted above, cholesterol cannot flow freely in the bloodstream), the presence of red blood cells with their high cholesterol content is likely the reason many studying CVD/CHD incorrectly believed that cholesterol itself was the primary cause of arterial plaque formation.
      • To expand on the first bullet above, arterial clotting that leads to CVD/CHD is not a single “cause and effect” problem but a process problem, and that process is triggered by at least one or a combination of the following factors – and more (as discussed in the book):
        • Smoking and exposure to airborne micro-particulate contaminants
        • Diabetes
        • Raised blood pressure
        • Chronic kidney disease
        • Rheumatoid arthritis
        • Severe mental illness
        • Systemic lupus erythematosus (SLE)
        • Atypical antipsychotic medication
        • Steroid medication
        • History of migraines

If you’ve gotten this far, please then look more closely at the caption under the YouTube screenshot at the top of this page regarding cholesterol and lifespan. If that caption and the short video interview you can see by clicking this link or the same screenshot picture, that pits Dr. Kendrick against a heart-diet hypothesis adherent, resonate at all with you, please read or listen to The Clot Thickens – or do both as I did. You’ll be greatly enlightened with extraordinary life-changing food and health common sense – and will certainly get what I mean by the last eight words in the paragraph below (and then do read the final NOTE at the bottom of the page, which surely got my attention).

Most of all, thank you, Dr. Kendrick for your integrity, inquisitive persistence and gutsy toughness blazing a trail focused on reducing CVD/CHD through common sense thinking and practice – all in the face of misguided and daunting academic, government and corporate opposition.

NOTE: Just before punching off this blog now, which took me days to write to get it right, I Googled the same query I started with at the top of this page, “does eating saturated fat cause heart disease”, and this time got a very different top hit titled A short history of saturated fat: the making and unmaking of a scientific consensus, first published online in December 2022 and posted by the same NIH National Library of Medicine that posted Facts about saturated fats noted above. What I find extraordinarily interesting is that the second article, “A short history of saturated fat”, is diametrically opposed to the first “Facts about saturated fats” article and provides a rigorous argument against the diet-heart hypothesis very similar to what Dr. Kendrick provides in his The Clot Thickens. I’m very glad to see that and now see hope regarding the daunting opposition I mention above, though, at the same, I certainly wonder how making that identical query within the timeframe of a few days resulted in a such a completely different response to my first Google query.

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